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96 Upon activation, phosphofructokinase 1 (PFK1) can bind to the transcription factor TEAD, stabilizing its interaction with YAP/TAZ in the nucleus, promoting YAP/TAZ transcriptional output, and impacting breast cancer progression

S., Schrder, K

Esses efeitos parecem ser mediados por alteraes nos padres de expresso gnica, em vez de agonismo direto do receptor

Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate

Nucleic Acids Res 40: 511-529

The vitamin B12TCN2 receptor, CD320, is downregulated in the brains of MS patients: this can then be restored by fingolimod that functionally antagonizes S1P1 and upregulates CD320, Chun and Kihara explained