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THE TARGET CONCENTRATION APPROACH TO DESIGNING A RATIONAL DOSAGE REGIMEN A rational dosage regimen is based on the assumption that there is a target concentration that will produce the desired therapeutic effect

van der Harst, P

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Oxytocin Differentiated effects according to the administration route in a prenatal valproic acid-induced rat model of autism

doi: 10.3390/ijms222111312 Summary Keywords depression, ferroptosis, signaling pathways, traditional Chinese medicine, acupuncture Citation Feng X, Zhang W, Liu X, Wang Q, Dang X, Han J and Zhang X (2025) Ferroptosis-associated signaling pathways and therapeutic approaches in depression

1962), low vitamin B6 levels is often related to depletion in neurotransmitters such as dopamine, serotonin, and -aminobutyrate due to its biochemical role as cofactor (PLP) for decarboxylases that are involved in neurotransmitter synthesis (Dakshinamurti and Stephens 1969)