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There is accumulating evidence that such psychosocial stressors activate oxidative stress pathways, thereby disrupting the oxidant-antioxidant balance within the brain and causing oxidative damage to DNA, mitochondria, lipids, and proteins

Our goal is to make these tools, and the resulting databases, generally available to the scientific community

Am J Med Genet (2002) 114:391406.10.1002/ajmg.10360 70 McDonaldCBullmoreETShamPCChitnisXWickhamHBramonEet alAssociation of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes

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An additional advantage of these procedures is that the elution volumes of refolded targets can be easily controlled (i.e., using smaller volume to elute) to avoid an extra concentration step for the final preparative protein liquid chromatography (Fig