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Modified GRF(1-29) without DAC has shorter duration of action (2-3 hours based on GHRH analog pharmacology) compared to the extended-release formulation

Sleep quality Studies since at least the 1990s have shown that higher GHRH activity can decrease wakefulness and increase slow-wave sleep.20 21 The relationship has to do with GHRH being necessary to slide you into the deepest sleep stages and keep you there.22 So the science supports using something like CJC-1295 to get more shut-eye

Published:

The Journals of Gerontology: Series A

However, researchers may consider the dosing used in trials with sermorelin due to the similarities with CJC-1295 no DAC

If using without DAC , dosing is usually daily , often at night, or more targeted timing such as pre-workout plus bedtime, depending on the protocol