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Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action

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CandelliMFranzaLPignataroGOjettiVCovinoMPiccioniAet alInteraction between lipopolysaccharide and gut Microbiota in inflammatory bowel diseases

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The peroxynitrite-induced overactivation of PARP leads to the consumption of NAD(+) and consequently, ATP, culminating in cell dysfunction, apoptosis or necrosis (Virg et al., 2003)