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In addition to regulating ferroptosis pathways, flavonoids also target multiple genes and signaling pathways, including nuclear receptors, aryl hydrocarbon receptor (AhR), kinases, receptor tyrosine kinases (RTKs), and G protein-coupled receptors (GPCRs) (Safe et al., 2021)

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10.1371/journal.pone.0036774 PLoS One 110 KudohK.UchinamiH.YoshiokaM.SekiE.YamamotoY

a temporary (i.e., reversible) inhibition of hematopoietic cell production which would aid the recipient in coping with exposure to extraterrestrial radiation levels

It results from damage to the nerves of the hands and feet, causing pain and loss of function

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