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Integrated result: The weighted polygenic score places the patient at a moderate-to-high risk (percentile ~8085%) for neurocognitive disorders, with greater susceptibility to frontotemporal lobar degeneration and late-onset Alzheimers disease

The intestinal UGT1A8 and UGT1A10 enzymes were suggested to have a negative impact on the bioavailability of orally administered therapeutic drugs (Mizuma, 2009)

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Translational Psychiatry, 2(7), e134