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Drug-induced peripheral neuropathy

Bevacizumab (Avastin), a humanized monoclonal antibody targeting the VEGF protein, has demonstrated substantial radiographic response (pseudo response), enhanced progression-free survival (PFS), and reduced corticosteroid need in patients with recurrent glioblastoma (rGBM)

As a result, one may age and develops illnesses associated with advanced age

Ganes L Z et

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Given its contrasting roles, therapeutic strategies targeting ferroptosis depend on disease context, aiming either to induce ferroptosis (e.g., in cancer) or inhibit it (e.g., in degenerative and ischemic diseases)