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Gating strategies are shown in Extended Data Fig

Los trabajos ms robustos se refieren a los efectos gastroprotectores y la cicatrizacin de tejidos blandos

Conditional deletion of Atg5 in OPCs precipitates apoptosis, inhibits differentiation, and results in significant hypomyelination, with surviving cells exhibiting cytoplasmic retention, swollen inner tongues, and myelin outfoldings

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5.2 FSP1-CoQ/DHODH-CoQ/GCH1-BH4/Nrf2-Keap1 signaling pathway In the last few years, three GPX4-independent signaling pathways have been identified to inhibit ferroptosis: Ferroptosis Suppressor Protein 1 (FSP1)/CoQ10, Dihydroorotic acid dehydrogenase (DHODH), and GTP Cyclic Hydrolyserase 1 (GCH1)/Tetrahydrobiopterin (BH4)