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Braz J Med Biol Res 45:546556 Schmidt-Sommerfeld E, Penn D, Kerner J, Bieber LL, Rossi TM, Lebenthal E (1989) Quantitation of urinary carnitine esters in a patient with medium-chain acyl-coenzyme A dehydrogenase deficiency: effect of metabolic state and l-carnitine therapy

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These changes were associated with a strong tendency toward increased extracellular L-glu levels as measured by microdialysis (Schallier et al., 2011)

Figure 1 provides a summary of the pathways and demonstrates which pathways are targeted by the better studied treatments