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F.PucciG.VettorR.et al (2021)

Skin Health: Grapefruit oil is a popular choice in skincare due to its astringent and antimicrobial properties

These metabolic benefits were accompanied by marked immunomodulatory effects, including reduced pro-inflammatory cytokines (TNF-, IL-1, IL-1), increased TGF-1, and trends toward elevated IL-10, leading to higher IL-10/TNF- and IL-4/TNF- ratios

& Hosoda, Y

Similarly, a growing number of studies found that SCFAs directly exerted positive effects on DN, including attenuation of renal damage, prevention of insulin resistance, and renal function impairment (84, 90, 133)