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Rajala RV, Datla RS, Moyana TN, Kakkar R, Carlsen SA, Sharma RK

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Lactate increases the action potential frequency of glucose-sensing neurons at the ventromedial hypothalamic nucleus via K ATP and chloride channels (Song and Routh, 2005)

Patients reach steady-state after approximately 4 weeks, therefore TDM within the first 4 weeks is not useful, except when a patients nonadherence is suspected

Selvakumaran M, Pisarcik DA, Bao R, Yeung AT, Hamilton TC

Xie Y, Mai CT, Zheng DC, He YF, Feng SL, Li YZ, et al