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doi: 10.1089/scd.2017.0123 60 XiongYZhangYXiongSWilliams-VillaloboAE

Presently, over 20 nanomedicines have received clinical therapeutic or diagnostic approval from the FDA or the European Medicines Agency (EMA), and an additional 75 clinical trials examining nanoparticles have been initiated in recent years [188]

These neuropsychiatric manifestations are often under-recognized and under-treated, yet they negatively affect daily functioning and overall well-being of PD patients 48,49,50

Thus, aging and various pathological conditions and human diseases, especially neurodegenerative diseases, are caused by biochemical changes in these macromolecular components, ultimately causing oxidative damage (78)

The stability, for up to 14 days, was carried out under various conditions, including different pHs buffers (68) and in the presence of glutathione (1 mM GSH), which is found in the cytosol of cells 49

Providers also keep track of behavioral changes, side effects, and overall health status