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To further validate this observation, we treated MTEC and 16HBE separately with cigarette smoke extract (CSE) and garlic oil, as well as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a compound also known as a key carcinogen in tobacco

10.1080/10408398.2016.1158690 92 MengQ.LuoL.LeiM.ChenZ.SunY.ChenX.et al (2023)

Moniruzzaman M, Ghosal I, Das D, Chakraborty SB (2018) Melatonin ameliorates H2O2-induced oxidative stress through modulation of Erk/Akt/ NFkB pathway

In this study, articular chondrocytes were expanded to a number that was needed for ACI

We have recently identified a set of 15 genes, called A nti-oxidant C apacity B iomarkers (ACB) which accurately predict the sensitivity of cell lines across various cancer types to redox-targeting drugs such as ferroptosis inducers (GPX4 inhibitors) or thioredoxin reductase 1 (TXNRD1) inhibitors 15

The IRB waived the need for written informed consent when it was previously obtained at entry into the SHAVE cohort