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However, there was no significant correlation between the change in plasma dUrd and platelet and leucocyte counts on either day 8 or 15

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S2CID 5916660

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For this reason, authors suggest an antioxidative therapy for patients with CF to diminish oxidative stress, thus reducing the risk of developing antibiotic resistance (Ciofu et al., 2005

While the Clade 2 GS enzyme tested clearly has a slower rate of canonical enzyme activity than the Clade 1 GS, it can nevertheless synthesise glutathione: It has a high affinity for the -EC dipeptide substrate, and a preference for glycine as the terminal amino acid despite a lack of conservation in the two residues that apparently contribute to this specificity