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Insulin-lowering agents in the management of polycystic ovary syndrome

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Myenteric neurons do not replicate in small intestine under normal physiological conditions in adult mouse

Andrade NP, Warner KA, Zhang Z, Pearson AT, Mantesso A, Guimaras DM, Altemani A, Mariano FV, Nunes FD, Nr JE

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Indeed, although our screen indicates a decrease in total cell count upon treatment, suggesting a cytotoxic effect, there was limited change to variant distribution, suggesting that there was a global decrease in the population rather than a specific sub-population of sensitive mutants