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These two changes together cause an important increase in bone density

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Thigh concerns Muscle injections: People with well-developed quadriceps or very low body fat on the thighs face a higher risk of accidentally injecting into muscle rather than subcutaneous tissue

Always keep the vials in their outer packaging until use to protect from light if instructed (though water itself is not light-sensitive, the packaging integrity is important)

Use an insulated travel case with ice packs to maintain 2-8 degrees Celsius during transport