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While it is not as common as other types of skin cancer (1% of skin cancers are melanoma) melanoma is more aggressive and is more likely to spread to other parts of the body, including the lymph nodes, lungs, liver, bones or brain

On account of the local or systemic adverse effects, increased surgical difficulty from intralesional medication, and insufficiency of high-level evidence, intralesional corticosteroids should not be recommended for treatment of PD (Russell et al., 2007)

Not only the area from which excess fat has to be removed is marked, but also the adjacent areas in which there is tissue deficiency

& Abdollahi, A

Physiol Rev (2019) 99(3):1381431

Nature 399(6735):483487