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Clinical trials did not include pregnant or breastfeeding women, children, elderly individuals over 65, or those with active malignancy or severe organ dysfunction

GIP is also implicated in nausea attenuation, which may be why GLP-1/GIP dual agonists like tirzepatide have a slightly better GI tolerability profile than pure GLP-1 agonists

These regulate metabolism, growth and other whole-body processes neuropeptides (endorphins)

Applied to the scalp, it can stimulate follicular activity, increase the size of hair follicles, and extend the anagen (growth) phase of the hair cycle to support density and thickness