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Nat Neurosci 21(3):309314 Liu J, Somera-Molina KC, Hudson RL, Dubocovich ML (2013) Melatonin potentiates running wheel-induced neurogenesis in the dentate gyrus of adult C3H/HeN mice hippocampus

The pathophysiology of advanced-stage lipedema remains poorly defined, and no validated biomarkers or targeted therapies are currently available

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These changes dramatically alter tumour microenvironment and cellular metabolism itself

Given the small sample size, paired non-parametric statistical analysis was performed using the Wilcoxon signed-rank test to assess changes in CARS scores pre- and post-intervention

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