10.1007/s11095-011-0476-8 Pharm
It is small, low molecular weight thiol tripeptide made up of glutamate, cysteine, and glycine
In HCC, CPS1 deficiency has been associated with altered SLC1A3 expression and intracellular aspartate homeostasis, thereby influencing tumor proliferation and metastatic behavior
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PMID: 168 LiuYGuoY-LMengSGaoHSuiL-JJinSet al
Interestingly, astrocytes (which protect neurons and promote sprouting) are activated because glial fibrillary acidic protein (GFAP) immunoreactivity increases in the striatum and indusium griseum upon METH treatment, thereby implying complex mechanisms involving guidance molecules and cytotoxic mediators in the neurotoxic consequences of METH (Ares-Santos et al., 2013
