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Collectively, these results suggested that the MN bandages could overcome the obstacles of local drug delivery in chronic wounds, delivering the drug directly to the site of action for therapeutic effect

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doi: 10.1186/s13059-016-1041-x 79 HataK.OkanoM.LeiH.LiE

That added component expands the blend into peptide-signaling, barrier-function, inflammatory-response, and cellular-response research contexts while still overlapping with recovery, repair, aesthetics, and longevity research categories

To identify IGF-1-mediated miRNA regulatory networks that cause temozolomide (TMZ) to be insensitive to glioblastoma multiforme treatment, on the basis of comprehensive analysis of multiple databases and in vitro experiments, Chen et al (104) confirmed that IGF-1 upregulated miR-513a-5p signaling reduced the sensitivity of glioma cells to TMZ by inhibiting the NEDD4L-inactivated Wnt/-catenin pathway

54772 pigmentary disorders, prevalence, impact on quality of life and social stigmatization: results of the first large international survey