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Introduction Neoplasms in the central nervous system (CNS) arise from various types of cells and make up about 2% of all cancers

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Human studies have used differing forms, doses and treatment periods

There are anecdotal reports of adverse effects such as injection site pain, anxiety, insomnia, headaches, dizziness, and gastrointestinal discomfort, but these are not well-documented in clinical studies

Although extensive research has focused on Ashwagandha root, the plants leaves are also abundant in withanolides, notably withaferin A, a compound recognized for its robust immunomodulatory and anti-inflammatory properties

We did not detect an increase in these markers in either ALI or non-ALI lungs in comparison with control lungs (Fig