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In some species, GH acts directly on androgen action, thereby accelerating the pubertal transition, because GH reduces the amount of testosterone required to induce secondary sexual characteristics (axillary hair) in young individuals [25]

A growth-hormone-releasing peptide dispensed as a take-home vial

doi: 10.1016/j.neuropharm.2015.01.027

An additional indicative point is sequential involvement

For pregnant women with chronic HBV infection, it is still unclear how the maternal immune system changes during pregnancy and postpartum, and whether this change will lead to changes in HBV infection status and disease progression