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Downregulation of VLDL receptor expression in chronic experimental renal failure

To trap the cholesterol within the HDL core, the HDL particle acquires the enzyme lecithin-cholesterol acyltransferase (LCAT) from the circulation (figure 6.10)

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13 In turn, during catabolism, Asn is hydrolyzed by aspartase to Asp, which is then aminated with -ketoglutarate to form glutamate and oxaloacetic acid