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Using oxygen consumption as a measure of mitochondrial function, NRTIs were shown to induce a rapid decrease in mitochondrial fitness

The relative standard deviations (RSD%) were calculated differential metabolites concentrations in the QC samples

Furthermore, we will report on recent advancements concerning iPSC-derived models used to unravel the metabolic contribution of astrocytes to neuronal demise

Most patients feel immediately better after one or two days, and then receive a boost every three or four months

These results indicate that TPC correlates more strongly with SOD and PPO, whereas TFC shows stronger correlations with GPX and CAT

Plasmid Construction pGEX-4T-1 was modified with a 6XHis tag in front of a GST tag at the N-terminus, and the thrombin protease cleave sequence was replaced by the TEV protease cleave site by a one-step site-directed deletion and insertion method [59]