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monocytogenes triggers the up-regulation of Ch25h in macrophages

a correlation analysis using Pearson's correlation was performed between the Vina docking scores and experimentally established IC50 for the respective compounds (Graphpad Prism 7.0, GraphPad Software Inc., La Jolla, Calif.)

This activation, driven by TMEM19 protein binding, was accompanied by the upregulation of angiogenic cytokines and growth factors, as well as neuroprotection, suggesting a new therapeutic function for erucamide in retinal diseases