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Each dot represents the placement of an orthologous gene along a given chromosome in each species (only genes from homologous chromosomes are shown)

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METALLURGY C07ORGANIC CHEMISTRY C07KPEPTIDES C07K2317/00Immunoglobulins specific features C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific CCHEMISTRY

Pharmacologic successes have unfortunately not kept pace with the increasing pathophysiologic insights into ALS, leading to only a few medications approved for use globally, none of which stop or reverse disease progression

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