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UPR, Unfolded Protein Response

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MVA was considered a safe and effective vaccine platform for use in elephants since it is replication-deficient in mammalian cells and has thus been attributed a high safety profile 33,34

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While each peptide has an independent body of preclinical literature, no published peer-reviewed study has examined this specific combination, and the theoretical synergy between their complementary mechanisms remains unvalidated by controlled experimental evidence

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