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[96] Animal models [edit] Animal studies try to mimic the disorder in humans by either modifying the Hypocretin/Orexin receptors or by eliminating this peptide

doi: 10.1046/j.1365-2265.2002.01654.x 28 LouwerensMAppelhofBVerloopHMediciMPeetersRVisserTet al

10.1038/s12276-018-0126-x 138

All the ex vivo and in vitro experiments have been carried out by blinded researchers in a randomized manner

Maternal L-Carnitine administration has been shown to reduce renal oxidative stress in SE offspring, but its effect in the brain is unknown

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