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By activating GLP-1 receptors in the brain, semaglutide GLP-1 enhances the feeling of fullness after meals, making it easier to control hunger and reduce overall calorie consumption

Clin Biochem2010;43:645649

The liver parenchyma exhibited mild activation of Kupffer cells and severe dilatation of sinusoids with liver congestion (Figure 12)

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Mechanism of action Peripheral 1 postsynaptic receptors are blocked, which causes vasodilation of both arteries and veins (indirect vasodilators)

Gupta, S