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However, he states that these effects are personal to his experience, and the efficacy of NAD+ supplements may vary across individuals

Efferth and Kaina, 2010)

The symptoms are more common at the start of treatment

The DESTINY-CRC01 trial exemplified this principle, achieving 45.3% objective response rate in HER2 IHC3 + /ISH + patients while observing no responses in HER2-low cohorts, highlighting the importance of stringent expression criteria