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Feary JR, Rodrigues LC, Smith CJ, Hubbard RB, Gibson JE

Fourth, insufficient data were available to determine the difference in efficacy of anti-inflammatory interventions on older participants with and without high-level baseline inflammation

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To examine the impact of mitochondrial damage, mRNA vaccines were administered to Polg +/D257A mice, which heterozygously express a proofreading-deficient mitochondrial DNA polymerase that sensitizes mitochondria to stress

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