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However, in addition to these reversible modifications, several cysteine adducts can form irreversibly due to prolonged exposure of cysteine residues to ROS and RNS, such as sulfinic or sulfonic acids (Chouchani et al., 2011

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Plant Cell Physiol 61:584595 McCord JM, Fridovich I (1969) Superoxide dismutase

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ORCID: Affiliation: 8 Neuroscience Theme, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney NSW 2006, Australia 9 Laboratory of Neurobiology and Pathological Physiology, Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, 602 00 Brno, Czech Republic These authors contributed equally to this work