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The reaction mixture was quenched with NH 4 Cl solution, extracted with EtOAc, dried over Na 2 SO 4 , concentrated to give #I5 as a light brown liquid (20 g, 95%) which was used for the next step without further purification

In addition, Owen and colleagues and Cho and colleagues observed that ECOG performance status was not associated with immune-related adverse events

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Popular Stack Combinations What Happens When You Stop Understanding what occurs after discontinuing the protocol helps set realistic expectations and informs decisions about cycling and long-term use