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It takes about 5% less energy to heat average seawater by 1 C than it does to heat the same mass of freshwater by 1C

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These methods all involve formation of an intermediate sulfonium species (R 2 S + OX) where X is a heteroatom attached to oxygen)

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All the 2D and 3D images of both the ligands and receptor were rendered in the free academic version of Maestro v12.6 tool of Schrdinger suite-2020.4 40