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Endothelium plays an important role in maintaining vasomotor, coagulation and anticoagulation systems, immune regulation, vascular smooth muscle proliferation and migration ( Figure 1 )

Since a thyroid nodule is commonly identified by physical exam or incidentally by an imaging technique (like CT or MRI) undertaken for another purpose, a thyroid ultrasound and a blood draw testing for hypothyroidism and hyperthyroidism is typically undertaken

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Furthermore, low serum enterolactone is associated with increased in vivo lipid peroxidation, assessed by plasma F2-isoprostane concentrations (Vanharanta et al., 2002)

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