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It disrupts the balance of the tumor immune microenvironment by synergistically regulating immune cells, precisely antioxidant, and relieving immune suppression, forming a microenvironment conducive to anti-tumor immunity, thereby exerting a powerful cancer immunotherapy effect and showing good biocompatibility and tumor accumulation characteristics [427, 428]

Glycine-based compounds may actually improve GI tolerability rather than worsening it

In contrast, patients who already demonstrated an adequate response to HBOT did not receive additional benefit from NAC administration, which directly supports the concept that NAC may be selectively advantageous in patients with pre-existing oxidative imbalance

The LMMs were adjusted for sex, height, BMI score (age-based BMI expressed as standard deviation score [BMI-SDS]), study centre and individual variation