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These modifications serve to make the molecule more resistant to degradation by dipeptidyl peptidase-4 (DPP-4) enzymes, which would otherwise break down the peptide structure

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It is billed as a concurrent infusion using a separate concurrent administration code

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As a result, eating a restrictive diet, such as a strict vegetarian or vegan diet, can lead to B12 deficiency

It is unknown whether MOUNJARO causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of tirzepatide-induced rodent thyroid C-cell tumors has not been determined [see Warnings and Precautions (5.1) and Nonclinical Toxicology (13.1)]