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Annu Rev Biochem 63:915948 Moller P, Wallin H (1998) Adduct formation, mutagenesis and nucleotide excision repair of DNA damage produced by reactive oxygen species and lipid peroxidation product

There is already ample evidence that ferroptosis does occur during neurodegenerative diseases, and the treatment of neurodegenerative diseases through targeting ferroptosis regulators has proven to be reliable

Cells 11:3439

What we have yet to completely understand is how these sequences are relevant to our biology (2)

In addition, the platforms capacity for multiplexed gene editing allows simultaneous modification of multiple therapeutic targets, enabling multifaceted MSC engineering, such as enhancing immunomodulatory capacity, tissue homing, or stress resistance