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A case report of biotin-thiamine-responsive basal ganglia disease in a Saudi child: is extended genetic family study recommended

In the two epilepsy models as mentioned above, the decrease of class I HDACs initiates the acetylation of histone H4 protein in rat hippocampal neurons and thereby activates the factors involved in epileptogenesis such as immediate early genes (IEGs) (e.g

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This should be kept in mind when designing experiments and interpreting the results of studies on drug-induced cell death mechanisms

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