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After NF-B translocates into the nucleus, it promotes the transcription of inflammatory genes such as ICAM-1 and E-selectin, which not only disrupts mitochondrial function but also leads to metabolic disorders (62)

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7.4.2 Community-engaged intervention design Effective interventions require understanding and respecting local contexts: Participatory research: Engage food processors, vendors, and consumers in identifying barriers to safer practices and co-designing culturally acceptable solutions

MOTS-c Mitochondrial-derived peptide commonly layered with Epithalon for cellular aging and metabolic depth

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