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As a result, increased FAO may lead to increased ROS production that then has a self-limiting effect on its own production by negative feedback

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Though there is not conclusive evidence comparing the extent of functional benefits provided by the 2 therapies, based on the data presented within the MAIC analysis of the drugs clinical trials, one can hypothesize that pegcetacoplan may have a greater effect than avacincaptad pegol on preserving visual function, and patients may be able to protect their driving and reading abilities for a longer period of time

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