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Rather than being limited to one specific area of research, it has become associated with studies spanning tissue biology, cellular communication, vascular biology and extracellular matrix research

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Among the developed PTX nanoformulations, the chimeric polypeptide-conjugated PTX (CPPTX) and poly-(-l-glutamylglutamine)-conjugated PTX (PGGPTX) nanoparticles were promising and were superior to Abraxane on PK profile and tumor drug exposure, rendering enhanced efficacy in various tumor models 11,18

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The resulting mitochondrial glutamate can exit the mitochondria into the cytosol, where this exported glutamate plays a role in the synthesis of important molecules, such as glutathione and non-essential amino acids (NEAAs)

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