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These pathological condi- tions hinder re- epithelialization and tissue regeneration, often resulting in chronic non- healing wounds with severe clini- cal outcomes, including amputation and increased mortality [8, 9]

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27,28 This weakening of the antioxidant defense system is further exacerbated by a reduction in dietary intake of crucial exogenous antioxidants found in fruits, vegetables, and whole foods which support and enhance our body's antioxidative capacity