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Prognostic value of metabolic imaging data of (11)C-choline PET/CT in patients undergoing hepatectomy for hepatocellular carcinoma

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Considering OS as one of the critical factors in LC development, antioxidant defense failure as a consequence of physiological aging may explain the increased occurrence of LC in the elderly and patients with already pre-existing cardiometabolic diseases, where is known that OS and inadequate antioxidant response due to decreased expression and/or activation of antioxidant enzymes are present (113)

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The cellular LMW thiols were alkylated by light (H 4 ) HPE-IAM and quantified by LC-MS by spiking a known concentration of LMW thiol derivatized by heavy D 4 -HPE-IAM as a standard

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