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44,45 In oesophageal squamous cell carcinoma, miR-455-3p participates in the activation of canonical Wnt signalling by simultaneously targeting and inhibiting multiple negative regulatory factors (e.g., DKK3 and GSK3) of the Wnt/-catenin signalling pathway

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Creagan ET, Moertel CG, O'Fallon JR et al (1979) Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer