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Despite unpredictable in most cases, the occurrence of AKI is significantly higher in severe I/R injury after kidney transplant surgery, cisplatin for tumor chemotherapy, or contrast media for radiography and so on, especially for the susceptible individuals, including old age and patients with diabetes mellitus or CKD (Zhang et al., 2020)

Shao K, Zhang Y, Ding N, Huang S, Wu J, Li J, et al

Product Introduction Ergothioneine (EGT) is a naturally occurring amino acid and is a thiourea derivative of histidine, containing a sulfur atom on the imidazole ring

To generate mito GCL (E103A), the forward and reverse oligonucleotides 5-CAGAGTATGGGAGTTACATGATT GCA GGGACACCTGGCCAGCCGTACGGA-3 (mutant nucleotides underlined) were used

Secondly, the objective to offer a broad overview of oxidative stress might have resulted in insufficient depth and detail regarding specific mechanistic insights, limiting a thorough examination of particular facets of the topic