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This fundamental difference implies that natural compounds might require less frequent dosing to achieve a continuous neuroprotective effect, whereas levodopa's dosing frequency is strictly determined by its short pharmacokinetics [101]

Such abnormalities have been reported in the ASD population previously 52, 53, 54 and zinc supplementation (along with B6) has been shown to decrease copper levels and improve function in ASD in an uncontrolled study

Frataxin gene point mutations in Italian Friedreich ataxia patients

doi: 10.1016/j.amjmed.2023.04.036 17 BrockJBasuNSchlachetzkiJSchettGMcInnesIBCavanaghJ

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