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Glutathione is built in two ATP-dependent steps (glutamate-cysteine ligase, then glutathione synthetase), used in redox and detox reactions, and later cleaved by gamma-glutamyl transpeptidase the only enzyme able to break its unusual gamma peptide bond

This universal conjunction, mediated by the IgG Fc region, can trap both viruses and bacteria in all major mucosal secretions 74

Productive oxidative protein folding in the ER critically depends on the supply of disulfide reductants, which are required to resolve mispaired disulfide crosslinks in folding substrates [59, 60]

Larger individuals may have more tissue for fat-soluble drugs to distribute into

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